Genetics of Fitness and Physical Performance

Capa
Human Kinetics, 1997 - 400 páginas

Genetics of Fitness and Physical Performance is the first comprehensive reference on the role of the genes in influencing individual variation in fitness and performance.

This essential compendium reviews the past 25 years of accumulated evidence on the genetic basis of health- and performance-related fitness phenotypes. Focusing on the interests of sport scientists, the authors provide insight into the significance of this research on nearly every aspect of the study of human physical activity.

The book presents the biological basis of heredity and explains the concepts and methods of genetic epidemiology and molecular biology that are necessary to understand this specialized field. With the rapid advances in molecular biology and the paradigms of human genetics, exercise scientists face a dynamic and vibrant new field. This book offers readers new opportunities to better understand atherosclerosis, noninsulin dependent diabetes, obesity, and hypertension by searching for single gene effects and identifying susceptibility genes.

The authors review the evidence on the role of the genes for human traits as it pertains to the exercise science field. And they explore the scientific, practical, and ethical issues that confront exercise scientists as progress is made in this field.

Genetics of Fitness and Physical Performance is vital reading for scholars in the field of exercise and sport science to understand how recent discoveries in genetics might shape their future research.

 

Índice

The International Effort to Study the Human Genome
8
Chapter 2The Human Genome
15
The Structure of
23
The Human Gene
29
Regulation of Gene Expression
36
Mutation and Genetic Variation
42
Detection of Genetic Variation
49
Summary
55
GeneticEnvironment Interactions
187
Genetics and Regional Fat Distribution
202
Summary
209
Chapter 11Genetics and Skeletal Muscle
221
GenotypeTraining Interaction Effects in Skeletal Muscle
232
Chapter 12Genetics of Cardiorespiratory
243
Genetics of Pulmonary Function
250
Summary
259

Chapter 4Understanding the Methods
59
Detection of Major or SingleGene Effects
70
Detection of GenotypeEnvironment Interaction
78
References
84
HealthRelated Fitness
90
Summary
97
Genetic Effects in Health Status
104
Summary
115
Genetics of Resting Metabolic Rate and Thermic Effect of Food
121
Summary
128
Chapter 8Genetics of Dietary Intake
131
Taste Preferences
139
Chapter 9Genetics of Body Size
149
Genetics and Morphological Phenotypes
155
Summary
168
Life Span Gender and Population Variability
177
Chapter 13Genetics of Metabolic Fitness
267
Glucose and Insulin
275
Other Risk Factors
281
Summary
287
Chapter 14Genetics and Motor
299
Summary
307
Overview of Genetic Studies
321
Chapter 16Molecular Medicine
353
Implications for HealthRelated Fitness
359
Chapter 17Genes and HighPerformance
365
Summary
371
Considerations for the Exercise Scientist
377
Index
386
About the Authors
399
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